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SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549
 

Schedule 13G/A

UNDER THE SECURITIES EXCHANGE ACT OF 1934
(Amendment No. 6)*

GTx, Inc.
(Name of Issuer)
Common Stock, $ 0.001 par value
(Title of Class of Securities)
40052B108
(CUSIP Number)
December 31, 2010
(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

     o Rule 13d-1(b)

     o Rule 13d-1(c)

     þ Rule 13d-1(d)

* The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

 
 

 

                         
CUSIP No.
  
40052B108 
 13G/A Page  
2 
   of   
5 
   Pages

 

           
1   NAME OF REPORTING PERSON
I.R.S. IDENTIFICATION NO. OF ABOVE PERSON (ENTITIES ONLY)

Mitchell S. Steiner, M.D., F.A.C.S.
     
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
  (a)   o
  (b)   o
     
3   SEC USE ONLY
   
   
     
4   CITIZENSHIP OR PLACE OF ORGANIZATION
   
  United States of America
       
  5   SOLE VOTING POWER
     
NUMBER OF   1,985,132
       
SHARES 6   SHARED VOTING POWER
BENEFICIALLY    
OWNED BY   841,284
       
EACH 7   SOLE DISPOSITIVE POWER
REPORTING    
PERSON   1,985,132
       
WITH 8   SHARED DISPOSITIVE POWER
     
    841,284
     
9   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
   
  2,826,416
     
10   CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (See Instructions) (a)  þ
   
  2,064,131(1)
     
11   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9
   
  5.6%
     
12   TYPE OF REPORTING PERSON (See Instructions)*
   
  IN
(1) Shares owned by Dr. Steiner’s spouse, as to which Dr. Steiner disclaims beneficial interest

 

                         
CUSIP No.
  
40052B108 
 13G/A Page  
3 
   of   
5 
   Pages
         
Item 1(a).
  Name of Issuer:   GTx, Inc.
 
        
Item 1(b).
  Address of Issuer’s   175 Toyota Plaza, 7th Floor,
 
  Principal Executive   Memphis, Tennessee 38103
 
  Offices:    
 
        
Item 2(a).
  Name of Person Filing:   Mitchell S. Steiner, M.D., F.A.C.S.
 
        
Item 2(b).
  Address of Principal   175 Toyota Plaza, 7th Floor,
 
  Business Office or, if none, Residence:   Memphis, Tennessee 38103
 
        
Item 2(c).
  Organization/Citizenship:   United States of America
 
        
Item 2(d).
  Title of Class   Common Stock, $0.001 par value
 
  Of Securities:    
 
        
Item 2(e).
  CUSIP Number:   40052B108
 
        
Item 3.
  Inapplicable.    
 
        
Item 4.
  Ownership.    
                                                 
    Total Shares                                
    of                                
    Common                           Sole   Shared
    Stock   Percent   Sole   Shared   Power   Power
    Beneficially   of   Voting   Voting   to   to
Person   Owned   Class(1)   Power   Power   Dispose   Dispose
Mitchell S. Steiner, M.D., F.A.C.S.
     2,826,416       5.6 %     1,985,132       841,284       1,985,132       841,284  
 
(1)   Based on 50,719,187 shares of Common Stock outstanding as of November 9, 2010 (as reported on the Company’s 10-Q for the quarter ended September 30, 2010).

 

 

                         
CUSIP No.
  
40052B108 
 13G/A Page  
4 
   of   
5 
   Pages
Item 5.   Ownership of Five Percent or Less of a Class.
  Inapplicable
Item 6.   Ownership of More than Five Percent on Behalf of Another Person.
  Inapplicable
Item 7.   Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company.
  Inapplicable
Item 8.   Identification and Classification of Members of the Group.
  Inapplicable
Item 9.   Notice of Dissolution of Group.
  Inapplicable
Item 10.   Certification.
  Inapplicable

 

 

                         
CUSIP No.
  
40052B108 
 13G/A Page  
5 
   of   
5 
   Pages
SIGNATURE
     After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
         
 
  2/14/2011    
 
  Date    
 
        
 
  /s/ Mitchell S. Steiner, M.D., F.A.C.S.    
 
       
 
  (Signature)    
 
        
 
  Mitchell S. Steiner, M.D., F.A.C.S.    
 
        
 
  Chief Executive Officer and Vice Chairman of the Board of Directors of GTx, Inc.